As we age, our ability to learn and form thoughts may become weaker and weaker. It is deterioration in cognitive function. New research showed that a compound found in grape seed extract can reduce plaque formation and resulting cognitive impairment in an animal model of Alzheimer's disease.
Grape seed extract, a byproduct of wine and grape juice production, contains high levels of powerful proanthocyanidin antioxidants. These molecules protect against sun damage, improve your vision, contribute to the flexibility of your joints and strengthen your blood vessels. Grape seed extract also improves brain function and may guard against some central nervous system conditions.
Previous studies suggest that increased consumption of grape derived polyphenols, whose content, for example, is very high in red wine, may protect against cognitive decline in Alzheimer’s.
The study appears in the June 18 issue of The Journal of Neuroscience. Lead study author Giulio Pasinetti, MD, PhD, of Mount Sinai School of Medicine and colleagues found that the grape seed extract prevents amyloid beta accumulation in cells, suggesting that it may block the formation of plaques. In Alzheimer's disease, amyloid beta accumulates to form toxic plaques that disrupt normal brain function.
Researchers orally administered a new grape seed extract to rats that are genetically predisposed to develop beta-amyloid plaques in their brains. These plaques are known to increase the risk of cell damage and death, leading to cognitive decline and a greater risk of developing Alzheimer’s disease.
Rats that had been given the grape seed extract underwent significantly less cognitive decline and had less in the way of beta-amyloid deposits.
The study suggested that grape seed-derived polyphenolics may be useful agents to prevent or treat Alzheimer’s disease.
Besides, a known compound resveratrol found in grape seed extract also has the unique ability to cross the blood-brain barrier and provide protection to an aging brain. Studies confirm that grape compounds are able to prevent damaging amyloid proteins from folding into structures that lead to dementia and Alzheimer~s disease.
Cognitive decline can be prevented by eating a diet void of processed foods, sugars and damaging hydrogenated fats. Eat a cup of wild blueberries each day and supplement with grape seed extract to provide critical antioxidant support and prevent the assault from free radical damage.
Grape seed extract is generally considered safe, but pregnant and breastfeeding women should avoid its use. In addition, grape-seed extract may act as a blood thinner, so it should not be taken with any blood-thinning medications, according to the University of Maryland Medical Center website.